Aglatimagene besadenovec
Aglatimagene besadenovec is a gene pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
7426 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Prostatic neoplasms | D011471 | — | C61 | 22 | 40 | 21 | 4 | 31 | 108 |
| Castration-resistant prostatic neoplasms | D064129 | — | — | 2 | 7 | 4 | 1 | 6 | 19 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasm metastasis | D009362 | EFO_0009708 | — | — | 3 | 1 | — | 2 | 6 |
| Recurrence | D012008 | — | — | — | — | 1 | — | 2 | 3 |
| Gynecomastia | D006177 | — | N62 | — | 1 | 1 | — | — | 2 |
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 5 | 5 | — | — | — | 7 |
| Adenocarcinoma | D000230 | — | — | 1 | 5 | — | — | — | 6 |
| Neoplasms | D009369 | — | C80 | 2 | 2 | — | — | 2 | 6 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 3 | 3 | — | — | 1 | 5 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 3 | 3 | — | — | — | 4 |
| Carcinoma | D002277 | — | C80.0 | 1 | 1 | — | — | 1 | 3 |
| Non-small-cell lung carcinoma | D002289 | — | — | 3 | 1 | — | — | — | 3 |
| Colorectal neoplasms | D015179 | — | — | 2 | 1 | — | — | — | 2 |
| Uterine cervical neoplasms | D002583 | — | — | 2 | 2 | — | — | — | 2 |
| Endometrial neoplasms | D016889 | EFO_0004230 | — | 1 | 1 | — | — | — | 1 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lymphoma | D008223 | — | C85.9 | 1 | — | — | — | — | 1 |
| Triple negative breast neoplasms | D064726 | — | — | 1 | — | — | — | — | 1 |
| Lung neoplasms | D008175 | — | C34.90 | 1 | — | — | — | — | 1 |
| Pharmacokinetics | D010599 | — | — | 1 | — | — | — | — | 1 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
| Pharmacological phenomena | D000069437 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Heart failure | D006333 | EFO_0003144 | I50 | — | — | — | — | 1 | 1 |
| Coronary disease | D003327 | — | — | — | — | — | — | 1 | 1 |
| Coronary artery disease | D003324 | — | I25.1 | — | — | — | — | 1 | 1 |
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | — | — | — | 1 | 1 |
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | — | — | — | 1 | 1 |
| Osteoporosis | D010024 | EFO_0003882 | M81.0 | — | — | — | — | 1 | 1 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | — | — | — | 1 | 1 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | — | — | — | — | 1 | 1 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Aglatimagene besadenovec |
| INN | aglatimagene besadenovec |
| Description | Aglatimagene besadenovec is a gene pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Gene |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL3544993 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 5Z72SSS34W (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Safety
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Adverse Events
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13 adverse events reported
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